I-LOAD, short for “Insulin
Load”, was designed to increase insulin sensitivity, and force carbohydrates,
amino acids, creatine, and other anabolic nutrients into muscle tissue.
Main benefits of I-LOAD™ Include:
Increase amino acid uptake in muscle tissue
Increase insulin receptor sensitivity
Increase glycogen storage in muscle tissue
Increase protein synthesis and DNA replication
Increase potassium uptake
-Increase blood flow
Decrease breakdown of protein
Enhance nutrient partitioning
How important is Insulin for building muscle?
Insulin is
the most powerful anabolic hormone in your body that has the ability to increase
protein synthesis, inhibit protein breakdown and transports glucose, amino acids
and creatine into muscle tissue.
Almost every amateur and professional bodybuilder is familiar with the power of
insulin due to the powerful glycogen pump it can produce along with
hyper-loading of nutrients post workout.
In addition, insulin also has a huge nutrient-partitioning effect,
driving food (and stored food energy) into building muscle instead of building
fat. The challenge with using prescription insulin is that if you make one bad
mistake it could cost you your life or put you into a coma.
Not good. So the key here is
to manipulate this powerful hormone without risking the dangerous side effects.
Why is insulin sensitivity important?
One of the key elements to managing the
power of insulin (and maintaining health), is to increase one’s insulin
sensitivity and also reduce the chance of becoming insulin resistance.
A person who is “insulin resistant” has a hard time processing
carbohydrates and their body releases a ton of insulin to get glucose into the
resistant cells. This “resistance”
is not a good thing, & overproduction of one’s own insulin can lead to type
2-diabetes which can cause kidney failure, blindness, arterial disease and
coronary heart disease. The key to
an efficient, healthy body is to increase insulin sensitivity where the body
doesn’t have to release a ton of insulin to get the glucose into the cell.
Insulin sensitivity is partly genetic and varies with each individual
usually peaking highest in professionally trained athletes.
Three of the best ways to increase insulin sensitivity is through
resistance training, cardiovascular training and manipulating one’s diet.(1)(2)
A moderate carbohydrate diet rich in Omega-3 fatty acids, fish oil and
fiber can make a dramatic impact upon one’s insulin sensitivity.
On the flip side, the low-carbohydrate, high-fat diets that have become popular
lately can decrease insulin sensitivity.
People should be very careful of these types of diets and limit their use
to a maximum of 3 weeks at a time especially if muscle gain is one’s preferred
goal.
How do I use I-LOAD™?
To feel the effects of a full-on glycogen
pump, take (1-2) capsules with your pre-workout meal or shake.
Meal or shake must contain at least 40-50 grams of carbohydrates
per capsule. For increased amino
acid & glucose uptake and speed recovery, take (1-2) capsules immediately
post-workout with at least 40-50 grams of carbohydrates per capsules.
Advanced users may take (1) additional capsule per day with a
carbohydrate rich meal. Do not
exceed 6 capsules per day unless you are facilitating pre-contest carb loading.
How does I-LOAD™ work?
There are quite a few supplements that
can help increase insulin receptor sensitivity and also drive glucose from the
blood and into the muscle cell. The
Glut-4 receptor inside your cell is the nutrient “gate keeper” that opens or
closes depending upon the amount of insulin that is present in the blood.
I-LOAD™ was designed to open up the Glut-4 flood gates & pull glucose out
of the blood and into the muscle.
This helps your body work more efficiently and keeps insulin sensitivity at its
maximum.
I-LOAD™ is not your simple ALA/chromium combination.
Utilizing cutting edge science, I-LOAD™ uses the following powerful
weapons to help keep insulin sensitivity at its maximum and store nutrients like
no other product currently on the market:
Banaba Leaf
Banaba Leaf Extract provides a
blood sugar lowering effect similar to that of insulin. It induces glucose
transport from the blood into body cells. Recently, researchers have isolated an
active ingredient in the banaba leaf called corosolic acid, which was originally
thought to be "the" blood sugar regulating substance in the leaf. A study
published in the journal Planta Medica in 2001 compared a whole-leaf extract of
banaba with insulin in cell cultures. The researchers concluded that the whole
herb has a glucose lowering effect. In other animal studies, administration of
banaba leaf extract resulted in reduced weight gain, reduced triglyceride
accumulation and reduced adipose tissue, with no changes in diet.
Gymnama Sylyestre
Originating from India, Gymnema Sylvestre is known
as gur-mar, or "sugar destroyer." Scientists think its active ingredients (gymnemic
acids) protect the cells of the pancreas from free radical damage, allowing them
to regenerate and produce insulin more effectively. A recent Harvard study
indicates the Gymnema lowers blood sugar levels in Type I and Type II diabetics.
At King's College in London, study stated that Gymnema acts by increasing cell
permeability, therefore reducing insulin resistance. Studies have shown that
gymnema can reduce glucose absorption from the intestine, help regulate blood
sugar levels and lower the amount of glucose available to be stored as fat.
When gymnema leaf is placed directly on the tongue,
it eliminates the sensation of sweetness. The leaves of Gymnema sylvestre
perform two significant functions. First, they suppress blood glucose,
especially after eating. Secondly, they are insulin tropic and promote insulin
secretion. By this multi-pathway approach, Gymnema sylvestre proves a valuable
aid in hyper-loading glucose into muscles.
Momordica 10:1 Extract
Bitter melon is the common
name for Momordica charantia, also known as African cucumber, balsam pear and
bitter gourd. The phytochemicals present in bitter melon suggest that there are
multiple uses for this herb. Among the constituents in bitter melon, charantin
is identified as an important agent for blood-sugar regulation. Charantin
demonstrates hypoglycaemic (blood sugar lowering). The Momordica fruit contain
insulin-like peptides, including one known as polypeptide P. In human studies,
bitter melon demonstrates significant blood-sugar control after food intake and
overall blood sugar-lowering effects.
In a study published in the
journal Chemistry & Biology- March 2008, a research team, headed by Dr. Mon-Jia
Tan of the Chinese Academy of Sciences in Shanghai, concluded that bitter melon
has potent anti-diabetes effects. In their study, Tan and colleagues isolated
and described several compounds from bitter melon known as cucurbitane
triterpenoids, and tested their effects on glucose (sugar) and fat metabolism in
cells and in mice. When tested in muscle and fat cells, the researchers found,
the compounds stimulated the glucose receptor GLUT4 to move from the cell
interior to the cell surface, thus promoting more effective glucose metabolism.
Several of the tested compounds had effects comparable to those of insulin.
Tests in mice of two of the compounds found that they promoted both glucose
tolerance and fat burning, and one was particularly effective in promoting
glucose tolerance in animals consuming high fat diets.
Momordica has been found to be
just as effective as glibenclamide in reducing blood sugar levels (J
Ethnopharmacol 2003; 88(1): 107-111). In fact, a large study at Harvard
University Medical School concluded that mormodica is one of the best natural
remedies for diabetes (Diabetes Care 2003; 26(4): 1277-1294). It appears that
mormodica contains compounds similar in structure to insulin, which have the
same effects in regulating blood sugar levels. There is evidence that mormodica
can prevent the release of excess glucose into the bloodstream from the liver
(Am J Health Syst Pharm 2003; 60(4): 356-359).
Chromium Polynicotinate
Chromium helps insulin
transport sugar to the cells. Chromium works to make insulin more effective by
"bridging" insulin to cell membranes, thus increasing the number of active
insulin receptors, resulting in increased insulin sensitivity. The trace mineral
chromium is found in skin, fat, muscle, brain and the adrenal glands. There is
about 6 mg in each of us and it is important! Chromium absorption through the
small intestine is very poor; so normally, a lot of it gets excreted in urine.
People with diabetes excrete even more chromium than healthy people; and the
loss of this vital nutrient makes it harder for their bodies to respond to
insulin. Studies show that chromium supplements can help both Type I and Type II
diabetics control their blood sugar.
There are various forms of
chromium suitable for human ingestion. The Polynicotinate form of chromium
called "Chromium
polynicotinate" is the most absorbable.
Chromium
polynicotinate is a unique molecule that
binds chromium with niacin, a compound found in breast milk, which helps the
body better absorb and process minerals.
In June of 2002, one form of
chromium was affirmed by the FDA as "Generally Recognized as Safe" (GRAS) for
use in food products, one of only a handful of ingredients to have secured this
status at clinically effective doses for use in foods marketed for weight loss
and glucose control.
How to use I-LOAD for pre-contest carb-up:
References:
*Sonksen PH 2001 Hormones and Sport.
Insulin, growth hormone and sport. Journal of Endocrinology
170, 13–25.
"As a natural body builder and cover model; I've
tried almost every thing to build quality muscle mass and get a sick pump.
Nothing I've tried comes close to I-Load & Pure Karbolyn. The pumps were
painful! I got a pump doing the dishes! Along with getting
visibly leaner, I put on 12lbs of lean muscle mass within a 30 day cycle of
using both products while following the SuperSize workout. Thank you
Professional Supplements to sticking to your guns and actually making QUALITY
products that work!"
I-Load